Bioinformatics

The Protein Data Bank (PDB) bioinformatics database is the world’s largest repository of experimentally-determined structures of proteins, nucleic acids, and complex assemblies. All data is gathered using experimental methods such as X-ray, spectroscopy, crystallography, NMR, etc. This article explains how to extract, filter, and clean data from the PDB to make it suitable for further analysis.

Genome data is one of the most widely analyzed datasets in the realm of Bioinformatics. The SciPy stack offers a suite of popular Python packages designed for numerical computing, data transformation, analysis and visualization, which is ideal for many bioinformatic analysis needs.

In this tutorial, Toptal Software Engineer Zhuyi Xue walks us through some of the capabilities of the SciPy stack. He also answers some interesting questions about the human genome, including: How much of the genome is incomplete? How long is a typical gene?