Toptal Blog

How do you approach machine learning problems? Are neural networks the answer to nearly every challenge you may encounter?

In this article, Toptal Freelance Python Developer Peter Hussami explains the basic approach to machine learning problems and points out where neural may fall short.

Hot module replacement is one of the most useful features offered by Webpack. It allows all kinds of modules, including JSON, CSS, and JS files, to be updated at runtime without needing a full refresh.

In this article, Toptal Freelance JavaScript Developer Shaojiang Cai demonstrates how to use Hot Module Replacement in Redux.

Biotech companies with little to no revenue can still be worth billions. Consider the most prominent 2017 biotech M&A deal when Gilead bought Kite Pharma for almost $12 billion. At the time of the deal, Kite had over $600 million in accumulated deficit, but it also had a pipeline of CAR-T cell therapies, which treat cancer. This article examines how to value such pipelines. It also focuses on the risk-adjusted NPV valuation methodology, portfolios of multiple drug candidates, and how value is impacted by the characteristics of the investor or acquirer.

Sketch is a valuable, time-saving resource for any designer’s toolbox. Though not every designer chooses to do so, creating style guides in Sketch can make it even more of a time-saver.

ASP.NET Core is a leaner and more modular redesign of ASP.NET 4.x.

In this article, Toptal Freelance ASP.NET Developer Damir Imangulov shows how to build a robust RESTful API using ASP.NET, EF Core, AutoMapper, and XUnit.

Major economic forces are shaping the Future of Work. Toptal sits down with executives from Seattle to hear their perspective on topics impacting companies across the US, including the talent gap and the looming threat of disruptive innovation.

Convertible notes have become an increasingly popular and common method for raising capital by startups, but how well do founders truly understand the implications of going down this route?

In this article, Toptal Management Consultant Jeffrey Briggs outlines the basics of convertible note structures, and runs through the pros and cons of using them to raise money for new entrepreneurial ventures.

AI has become an over-hyped buzzword and the design world is no exception. Instead of resisting it, designers will soon be co-creating with AI. It will make them smarter. (Includes infographic)

Crystal is an up and coming programming language that should appeal to Ruby veterans in demand for more performance and flexibility. It may even be the most promising programming language of 2018.

In this tutorial, Toptal Ruby Developer Eqbal Quran demonstrates how you can harness Crystal’s potential to create your own blockchain and cryptocurrency.