Toptal Blog

The Protein Data Bank (PDB) bioinformatics database is the world’s largest repository of experimentally-determined structures of proteins, nucleic acids, and complex assemblies. All data is gathered using experimental methods such as X-ray, spectroscopy, crystallography, NMR, etc. This article explains how to extract, filter, and clean data from the PDB to make it suitable for further analysis.

Although employee tenures are decreasing, innovative companies embrace the trend as an opportunity to maximize impact. In this article, Andy Anderson, a Toptal Client Partner, shares perspective on how such companies view - and capitalize on - employee attrition.

The field of robotics has seen incredible strides forward in recent years. As a result of improvements in computer vision, dexterity and also overall economics, use of robots has increased in a variety of different fields. However, most of the growth in robotics so far has happened in industrial applications, and thus hidden from the view of the general public. But is this about to change?

In this article, Toptal Management Consultant Francesco Castellano focuses on the commercial robotics market. Thanks to recent breakthroughs in the fields of AI, mechatronics, sensors, and batteries, service and commercial robots are likely to see tremendous growth and adoption, likely heralding a new robotics revolution that could transform our daily lives in countless ways.

CSS is notorious for getting messy quickly as a website scales. While frameworks like Bootstrap can help, SMACSS takes a different approach, as a set of solid organizational guidelines. In this article, Toptal Freelance Front-end Developer Slobodan Gajic gives us a run-down of the idea and benefits behind Jonathan Snook’s architectural wisdom.

UI and UX designers must work in tandem in order to create a finished product that delights users both visually and functionally.

Employing Python to make machine learning predictions can be a daunting task, especially if your goal is to create a real-time solution. However, Tensorflow and Scikit-Learn can significantly speed up implementation.

In this article, Toptal Python Developer Guillaume Ferry outlines a simple architecture that should help you progress from a basic proof of concept to a minimal viable product without much hassle.

Conventional wisdom says you need a team to found a startup. But what if you prefer to do it alone or can’t find the right co-founders? Contrary to popular belief, there are many successful solo ventures. This guide shows you how to get started.

Many businesses use SharePoint but use it poorly. Restructuring and re-education are the keys to getting the most out of SharePoint. In this article, Toptal Freelance SharePoint Developer Anthony Lucidi explores how features like metadata tags, SharePoint workflows, and PowerApps can make a world of difference.

How does Figma improve the design process and outperform Sketch and other design tools when it comes to designer collaboration? Learn the big differences that every designer should know.